Genetically engineered synthesis of natural products.

نویسنده

  • A I Scott
چکیده

The feasibility of multi-step, one-flask total synthesis of natural products is demonstrated by cloning and overexpression of the corresponding biosynthetic enzymes from plant and microbial sources. As many as eight or nine enzymes can be recombined in vitro to reach an advanced intermediate in the vitamin B12 pathway.

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عنوان ژورنال:
  • Journal of natural products

دوره 57 5  شماره 

صفحات  -

تاریخ انتشار 1994